I ran across a workstation that is very similar to mine using the same software, Cintiq and monitor configuration. The big difference is that I don't have to reach over my drawing to get to my keyboard and that surprisingly makes a real difference.
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You can see my system, on the left with the yellow sub on the monitor, can dock menus on the large monitor and leave the Cintiq free for drawing. My Cintiq is elevated and at a comfortable height and angle for drawing and my keyboard is mounted underneath which is ergonomically better and keeps me from stretching over my drawing to get to.